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Tbio
VSNL1
Visinin-like protein 1

Protein Summary
Description
Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner. This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295156
  • ENSP00000295156
  • ENSG00000163032
  • ENST00000404666
  • ENSP00000384014
  • ENST00000406397
  • ENSP00000384719

Symbol
  • VISL1
  • HLP3
  • VILIP
  • HPCAL3
  • HUVISL1
  • VILIP-1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.86
virus perturbation
0.76
protein domain
0.73
interacting protein
0.72
transcription factor
0.6


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 104.09   (req: < 5)
Gene RIFs: 41   (req: <= 3)
Antibodies: 1130   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 104.09   (req: >= 5)
Gene RIFs: 41   (req: > 3)
Antibodies: 1130   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0