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Tdark
BTBD11
Ankyrin repeat and BTB/POZ domain-containing protein BTBD11

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000280758
  • ENSP00000280758
  • ENSG00000151136
  • ENST00000357167
  • ENSP00000349690
  • ENST00000420571
  • ENSP00000413889
  • ENST00000490090
  • ENSP00000447319
  • ENST00000494235
  • ENSP00000448322

Symbol
  • ABTB2B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.85
transcription factor perturbation
0.84
transcription factor
0.79
transcription factor binding site profile
0.76
PubMedID
0.71


Related Tools
Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.91   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 6   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.91   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 6   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
1
1
1
0.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte percentage of leukocytes
1
0.2
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
BTB domain containing 11
VGNC:12798
452206
Macaque
BTB domain containing 11
704916
Mouse
MGI:1921257
74007
Rat
RGD:1308647
314675
Dog
BTB domain containing 11
VGNC:38547
481292
Species
Name
OMA
EggNOG
Inparanoid
Chimp
BTB domain containing 11
Macaque
BTB domain containing 11
Mouse
Rat
Dog
BTB domain containing 11
Protein Structure (0 Structures, 1 AlphaFold Model)
RepresentationColor Scheme
AF-A6QL63-F1-model_v1

AlphaFold Structures Developed by DeepMind and EMBL-EBI

Gene Ontology Terms (3)
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Protein-Protein Interactions (73)
1 – 10 of 73
ABTB2
Tdark
Novelty: 0.45729157
p_int: 0.999999356
p_ni: 6.14e-7
p_wrong: 3e-8
Score: 0.54
Data Source: BioPlex,STRINGDB
PPFIBP1
Tbio
Novelty: 0.09685089
Score: 0.781
Data Source: STRINGDB
TSPAN9
Tbio
Novelty: 0.17982192
Score: 0.654
Data Source: STRINGDB
GSTT2B
Tbio
Family: Enzyme
Novelty: 0.02334158
Score: 0.621
Data Source: STRINGDB
STAB2
Tbio
Novelty: 0.01141869
Score: 0.582
Data Source: STRINGDB
TIGAR
Tbio
Family: Enzyme
Novelty: 0.0090389
Score: 0.582
Data Source: STRINGDB
ASNSD1
Tdark
Family: Enzyme
Novelty: 0.54006324
Score: 0.579
Data Source: STRINGDB
ASDURF
Tdark
Novelty: 0.54006324
Score: 0.579
Data Source: STRINGDB
NUAK1
Tchem
Family: Kinase
Novelty: 0.01730498
Score: 0.569
Data Source: STRINGDB
FBXL19
Tbio
Novelty: 0.07526966
Score: 0.562
Data Source: STRINGDB
Publication Statistics
PubMed Score  0.91

PubMed score by year
PubTator Score  0.51

PubTator score by year
Amino Acid Sequence
Residue Counts
Protein Sequence
ProtVista Viewer