Mondo Description A malignant, invasive embryonal neoplasm arising from the cerebellum. It occurs predominantly in children and has the tendency to metastasize via the cerebrospinal fluid pathways. Signs and symptoms include truncal ataxia, disturbed gait, lethargy, headache, and vomiting. There are four histologic variants: classic medulloblastoma, large cell/anaplastic medulloblastoma, desmoplastic/nodular medulloblastoma, and medulloblastoma with extensive nodularity.
Uniprot Description Malignant, invasive embryonal tumor of the cerebellum with a preferential manifestation in children.
Disease Ontology Description An infratentorial cancer that is located_in the lower part of the brain and is a type of primitive neuroectodermal tumor.